Phenomics Australia Histopathology and Digital Slide Service
Welcome to the Phenomics Australia Histopathology and Slide Scanning Service website
Supported by Phenomics Australia
The Phenomics Australia Histopathology & Slide Scanning Service provides necropsy and histopathology services to all biomedical researchers across Australia for evaluating or phenotyping modified, treated, experimental or genetically engineered mice at all developmental stages.
A team of experienced medical, veterinary pathologists and mouse pathobiologists determine whether morphological changes or pathology identified are strain-related, age-related, incidental or a true diversion from normal. The mouse strains are therefore validated and utilised as models of human disease.
The Histopathology and Digital Slide Service is based at the Department of Anatomy and Physiology at the University of Melbourne and is supported by the Federal Government through the National Collaborative Research Infrastructure Strategy (NCRIS) initiative and by the University of Melbourne.
Our standardised procedures are designed to provide a thorough, first-line approach to assessing the entire animal or organs of interest.
Evaluations
- Professional commentary from medical and veterinary pathologists and mouse pathobiologists
- Necropsy and full-body histopathology (rodent)
- Semi-quantitative analysis-Tissue Scoring
- Mouse neonates and embryos
- Blood and bone marrow smears
- Terminal blood analysis
Request service here (iLab)
Imaging
- High-quality, high-speed brightfield slide scanning (slide digitization)
- Macroscopic/microscopic image documents accompanying all Histopathology reports
- Secure online access to all digitized images and histopathology reports
The Histopathology and Digital Slide Service provides a secure interface where users can login and interrogate their case files, reports and images.
To view your images access slides.
Tissue Scoring and Grading
Through experience and careful collaboration with our pathologists and researchers, our service has developed standardised protocols to enable a semi-quantitative approach to evaluate the effects of treatments. These protocols are unique to each tissue and can be project specific.
Data Curation
Secure online access to large format, interrogable histological images created utilising state-of-the-art image acquisition systems.
Access SlideCenter here
The Platform is a fee-for-service operation, open to all not-for-profit and corporate requests.
Staff are always available to assist.
Complementary platform technologies/services:
Terms & Conditions
Read the terms and conditions (DOCX 32.1 KB)
Tina Cardamone
Node manager
Email: t.cardamone@unimelb.edu.au
Professor Janet Keast
Phenomics Australia Histopathology and Digital Slide Service Unit Leader
Email: janet.keast@unimelb.edu.au
General Email: histopathology-scanning@lists.unimelb.edu.au
Location:
Room E236,
Department of Anatomy and Physiology,
Medical School Building (Corner of Grattan Street and Royal Parade),
University of Melbourne
Consulting Pathologists
Phenomics Australia has access to leading diagnostic and academic pathologists.
- Professor Catriona McLean
Medical Pathologist &
Head of Department
of Anatomical Pathology,
The Alfred Hospital - Dr John Finnie
Senior Comparative Pathologist,
The University of Adelaide,
South Australia - Dr Lorna Rasmussen
Specialist Veterinary Pathologist,
Melbourne, Victoria
Governance
At a national level, Phenomics Australia has an independent Governance Board established to provide oversight and strategic guidance to the Chief Executive Officer and the Management Group. The board members provide a solid and broad experience in scientific strategy, biomedical research, policy, governance, industry engagement and commercialisation. Phenomics Australia Histopathology and Slide Scanning Service, University of Melbourne has a 4 member local management committee comprised of Professor Janet Keast, Professor John Furness, Dr Dagmar Wilhelm and Ms Tina Cardamone.
Phenomics Australia Histopathology and Digital Slide Service
Histological investigation of mutant or treated experimental mice
This service provides a necropsy investigation, where 30 standard organs and tissues are histologically analysed. Special investigations can be ordered upon request.
3D Histech Pannoramic ScanII Scanner
This is a high resolution scanning device capable of imaging standard stained histological slides. Digital images can be interrogated by the client with the Case Viewer software https://www.3dhistech.com/software-downloads
(Note: software is only compatible with windows operating systems). Users have the option to either collect and copy their images or for a small fee access and view their images via the Case Center web interface
MetaSystems V-Slide Scanner
Is a microscope based slide scanning system with brightfield and fluorescence capture, generating digitised high resolution whole slide images. It is fitted with low and high power objectives including a 5x, 40x dry & 63x oil and has six channels capable of imaging DIC, DAPI, FITC, TR, Cy3 and Cy5.
Scanned images can be collected directly from the Scanner.
These scanners are part of Phenomics Australia and are also available to external users.
Digital images can be interrogated using VSViewer.
This is not compatible on a Mac operating system.
Histopathology and Slide Scanning Standard Operating Procedures
For standard operating procedures please contact the Histopathology and Digital Slide Service directly histopathology-scanning@lists.unimelb.edu.au
Location
Department Anatomy and Neuroscience
Room E237b, Level 2, Medical Building
The University of Melbourne
Contacts for access
Tina Cardamone: +6 3 834 48044
Aira Nuguid: +61 3 834 47646
histopathology-scanning@lists.unimelb.edu.au
Facility hours
Monday – Friday: 8.30am to 5.00pm
The Scanners are not available on weekends
Services
Clients have the option of Staff Service or unassisted scanning after undertaking a training session. This can be arranged with Tina Cardamone or Aira Nuguid.
Email: histopathology-scanning@lists.unimelb.edu.au
Booking
Online bookings may be made using Google Calender Service. Access to the calendar, including logins and passwords, is provided to all approved users once training has been completed.
Charges
Please contact histopathology-scanning@lists.unimelb.edu.au for charge schedules and quotes.
Training
All unassisted users must attend an initial training session.
This is organised through the Phenomics Australia manager and incurs a fee.
Note: Prices subject to change
Sessions may be cancelled at any time to schedule maintenance or repairs.
Notice will be issued where possible, but occasionally there will be no notice period.
The Histopathology and Digital Slide Service is supported by Phenomics Australia
The Histopathology and Digital Slide Service provides a secure interface where users are able to login and interrogate their case files and images
To access your slides on the SlideCenter viewer you will need your login details: user name and password
Access slides-SlideCenter viewer