Importance More than 100 million units of blood are collected worldwide each year, yet the
indication for red blood cell (RBC) transfusion and the optimal length of RBC storage prior to
transfusion are uncertain. Objective To provide recommendations for the target hemoglobin
level for RBC transfusion among hospitalized adult patients who are hemodynamically
stable and the length of time RBCs should be stored prior to transfusion. Evidence Review
Reference librarians conducted a literature search for randomized clinical trials (RCTs) …