Delivering drug discovery via our unique display technology
Peptide
Discovery
Peptide Display
What we do
Orbit Discovery offer services for the discovery of peptides and our technologies have been used to identify peptides as the starting point for peptide conjugates, functional peptides, peptidomimetic and small molecule therapeutics.
Our services have been used to identify peptide hits for radionuclide targeting, nucleic acid targeting, components for targeted protein degraders and for GPCR agonists. These applications have been served by a combination of bead based technologies and microfluidics. This combination facilitates high throughput screening and allows the interrogation of a large chemical space. The platform can be configured for affinity screening (targeting binders), but can also be configured for direct functional screens (in particular for agonists) using internally designed reporter cell lines.
Orbits mission is to offer our Partners solutions to identify peptide therapeutic hits by adopting high throughput affinity and functional screening.
Affinity Screening Service
A bead based peptide display engine, using FACS, allows for faster peptide discovery by binding affinity.
Functional Screening Service
The ability to display high peptide copy number allows discovery of functional peptides, such as agonists and antagonists, in primary screens
Target Production Services
The Orbit platform is target agnostic giving access to cell surface receptors, notably GPCRs and ion channels. We have a dedicated team focused on production of targets to ensure quality of starting materials
Single Cell Reporter Assay Services
Using expertise in cell line development and assay development, in conjunction with FACS, high content imaging and microfluidics, the Orbit platform can distinguish a functional response from single cells
Establishing a new standard
Orbit works with both industry and academic Partners to identify hits for existing and novel drug targets where therapeutic peptides can establish a new standard of care.
Find out how Orbit can help you with peptide discovery
